隐球菌病多起始于肺部,继而向其他内脏播散,尤其是脑膜和脑。10％病人有皮肤损害,表现为多发性小丘疹,结节,痤疮样脓疱,皮下肿胀,丹毒和溃疡等。无其他脏器或全身累及的原发性皮肤隐球菌病罕见,作者报告一例。患者男,53岁。1983年6月右手腕发现生长迅速的硬性块状物4周,曾因哮喘自服强的松龙每日～10mg达10余年。1975年左手掌患手癣,1977年患花斑癣。患者喂鸽子数年,发病前无外伤史。检查:环绕右腕有一边界清楚8×12cm红斑鳞屑性 Cryptococcosis often starts in the lungs, which in turn spreads to other organs, especially the meninges and brain. 10% of patients have skin lesions, manifested as multiple papules, nodules, acne-like pustules, subcutaneous swelling, erysipelas and ulcers. No other organ or systemic involvement of primary cutaneous cryptococcosis rare, the authors report a case. Male patient, 53 years old. In 1983 June the right wrist found rapid growth of hard lumps for 4 weeks, had asthma self-serving prednisolone ~ 10mg daily for 10 years. Left hand palm suffering from ringworm in 1975, 1977 suffering from tinea versicolor. Patients fed pigeons for several years, before the onset of no history of trauma. Check: a border around the right wrist clear 8 × 12cm erythema scaly