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优选目的:速尿治疗肝硬化腹水,剂量小达不到治疗效果,剂量过大易产生水与电解质紊乱,为此选择用药最佳剂量。优选方法:单因素0.618法优选范围:40mg/M~2—120mg/M~2 ①(120mg/M~2～40mg/M~2)×0.618+40=89.88mg/M~2 ②120mg/M~2+40mg/M~2-89.88mg/M~2=70mg±/M~2(优) 优选结果:应用70mg/M~2剂量×1.26M~2(体重为38Kg,体表面积1.26M~2)=90mg/
Optimal purpose: Furosemide treatment of cirrhosis and ascites, small dose of less than the therapeutic effect, excessive dosage easy to produce water and electrolyte disorders, choose the best dose for this purpose. Preferred method: single factor 0.618 method Preferred range: 40mg / M ~ 2-120mg / M 2 ① 120mg / M ~ 2 ~ 40mg / M ~ 2 × 0.618 + 40 = 89.88mg / M ~ 2 120mg / M ~ 2 + 40mg / M ~ 2-89.88mg / M ~ 2 = 70mg ± / M ~ 2 (excellent) Preferred results: 70mg / M ~ 2 dose × 1.26M ~ 2 (body weight 38Kg, body surface area 1.26M ~ 2 ) = 90 mg /