目的　探讨北京市围产儿死亡变化规律及干预措施成效。　方法　采用流行病学前瞻性研究方法，对１９８８ 至１９９７ 年围产儿死亡情况连续监测，进行动态数列分析。　结果　１９８８ 年围产儿死亡率１５ ．７３ ‰，１９９７ 年１０ ．９３ ‰，下降显著。下降速度大约每隔３ 年下降１０％ 。围产儿死亡原因主要是畸形、新生儿疾病、胎儿因素、脐带因素等。死胎死产主要死因为脐带缠绕、胎儿窘迫、胎盘早剥等，早期新生儿主要死因为早产、窒息、吸入性肺炎等。前后五年主要死因死亡专率有明显下降，如神经管畸形、早产、窒息、吸入性肺炎、胎儿窘迫。死亡评审结果：可避免及创造条件可避免城市占２５ ％ ，农村占４１％ 。　结论　十年来北京市采取的降低围产儿死亡的各项干预措施是科学的、有效的，２０００ 年实现ＮＰＡ 目标是可能的 Objective To investigate the changes of perinatal mortality and the effectiveness of interventions in Beijing. Methods By epidemiological prospective research methods, continuous monitoring of perinatal deaths from 1988 to 1997 was conducted, and the dynamic series were analyzed. Results Perinatal mortality in 1988 15. 73 ‰, 1997 10. 93 ‰, a significant decline. The rate of decline drops about 10% every three years. Perinatal deaths are mainly deformities, neonatal diseases, fetal factors, umbilical cord factors. The main cause of death from stillbirths is umbilical cord entanglement, fetal distress and placental abruption. The main causes of death in early neonates are premature birth, asphyxia and aspiration pneumonia. Five years before and after the death of major causes of mortality decreased significantly, such as neural tube defects, premature birth, asphyxia, aspiration pneumonia, fetal distress. Death Assessment Results: avoidable and create conditions to avoid 25% of cities, rural areas accounted for 41%. Conclusions The interventions taken to reduce perinatal deaths in Beijing over the past decade are scientific and effective and it is possible to achieve NPA targets in 2000