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目的观察β受体阻滞剂对心力衰竭的临床疗效。方法将入选患者随即分为两组。两组性别、年龄、病因及基础用药具有可比性。对照组给予强心利尿扩血管等常规治疗。治疗组在常规治疗的基础上,加服β受体阻滞剂(卡维地洛),对治疗前后心率(HR)、血压(BP)、左室舒张末期内径(LVDD)、左室射血分数(LVEF)对比观察。结果治疗组较对照组心功能各项指标均明显好转。结论在常规强心、利尿、扩血管治疗顽固性心衰的基础上,加用β受体阻滞剂,能迅速缓解慢性心力衰竭急性加重期临床症状,缩短住院日程;长期用药能抑制心肌重塑,改善心功能,提高射血分数,降低病死率。
Objective To observe the clinical effect of β-blocker on heart failure. Methods Patients were randomly divided into two groups. Two groups of gender, age, etiology and basic medication is comparable. Control group given cardiac diuretic vasodilators and other conventional treatment. On the basis of routine treatment, the patients in the treatment group were given β-blocker (carvedilol) before and after treatment. The heart rate (HR), blood pressure (BP), left ventricular end diastolic diameter (LVDD), left ventricular ejection Score (LVEF) contrast observation. Results The treatment group than the control group, cardiac function indicators were significantly improved. Conclusion The conventional cardiac, diuretic, vasodilator treatment of intractable heart failure, based on the addition of β-blockers, can quickly alleviate the clinical symptoms of acute exacerbation of chronic heart failure, shorten the hospitalization schedule; long-term medication can inhibit myocardial weight Plastic, improve heart function, improve ejection fraction, reduce mortality.