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目的探讨甲状腺球蛋白抗体(TgAb)、甲状腺过氧化物酶抗体(TPOAb)在桥本氏甲状腺炎(HT)合并甲状腺乳头状癌(PTC)患者中的浓度变化。方法采用化学发光法检测100例HT合并PTC患者(A组)、100例HT合并良性结节患者(B组)血清中TgAb、TPOAb的浓度,分析其对HT合并PTC的影响。结果A组TgAb、TPOAb区间浓度数值高的发生率高于B组(P<0.05)。结论对于血清中TgAb、TPOAb浓度升高的HT合并甲状腺结节患者,应该加强随访,定期复查。
Objective To investigate the changes of thyroid globulin antibody (TgAb) and thyroid peroxidase antibody (TPOAb) in patients with Hashimoto’s thyroiditis (HT) and papillary thyroid carcinoma (PTC). Methods The concentrations of TgAb and TPOAb in 100 cases of HT patients with PTC (group A) and 100 cases of HT patients with benign nodules (group B) were determined by chemiluminescence. Results The incidence of high concentration of TgAb and TPOAb in group A was higher than that in group B (P <0.05). Conclusions Patients with HT combined thyroid nodules with elevated levels of serum TPAb and TPAb should be followed up and reviewed regularly.