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目的 探讨多发性硬化 (MS)的临床特点以及诱发电位 (EP)、磁共振成像 (MRI)对MS的诊断价值。方法 分析 35例MS患者的临床表现及视觉诱发电位 (VEP)、体感诱发电位 (SEP)、脑干听觉诱发电位 (BAEP)和MRI的检查结果。结果 MS多见于青壮年 ,女性多见 ,呈急性或亚急性起病 ,视神经、脊髓、脑干受累多见 ,病程多缓解复发。VEP、SEP、BAEP、头颅MRI、脊髓MRI检查的异常率分别为 81.5 %、76 .2 %、5 2 %、77.8%、87.5 %。结论 MS的诊断主要依靠临床 ,EP和MRI检查对MS患者临床病灶的确定和亚临床病灶的发现均具有较高的敏感性 ,二者结合应用可显著提高MS的诊断正确率
Objective To investigate the clinical features of multiple sclerosis (MS) and the diagnostic value of evoked potential (EP) and magnetic resonance imaging (MRI) in MS. Methods Clinical manifestations and visual evoked potentials (VEP), somatosensory evoked potential (SEP), brainstem auditory evoked potentials (BAEP) and MRI findings in 35 patients with MS were analyzed. Results MS more common in young adults, more common in women, was acute or subacute onset, optic nerve, spinal cord, brain stem involvement more common, course of disease relief and recurrence. The abnormal rates of VEP, SEP, BAEP, cranial MRI and spinal cord MRI were 81.5%, 76.2%, 52%, 77.8% and 87.5% respectively. Conclusion The diagnosis of MS mainly depends on the clinical, EP and MRI examination of MS patients to determine the clinical lesions and subclinical lesions were found to have high sensitivity, the combination of the two can significantly improve the diagnostic accuracy of MS