泼尼松和泼尼松龙是一种泼尼松的活性代谢物,二者早在1956年即开始用于儿童肾病综合征。至今,糖皮质激素(简称激素)仍是目前治疗原发性肾病综合征(NS)的首选药物和基本药物。泼尼松很快代谢为泼尼松龙,因而2种制剂都可选用,但有肝功能受损时最好选用泼尼松龙。它们胃肠道吸收很 Prednisone and prednisolone, an active metabolite of prednisone, have been used in childhood nephrotic syndrome since 1956. So far, glucocorticoid (referred to as hormone) is still the treatment of primary nephrotic syndrome (NS) of choice for drugs and essential drugs. Prednisone is rapidly metabolized to prednisolone, which can be used in both formulations, but prednisolone is best used when liver damage is impaired. They are absorbed in the gastrointestinal tract