妊娠期高血压疾病是导致孕产妇和围产儿发病和死亡的主要原因之一,其病因尚不明确。近年来对妊娠期高血压疾病的研究发现,滋养层细胞对子宫内膜的侵蚀不足是其发病的主要原因[1]。滋养细胞的生理功能包括增殖、分化和迁延(侵蚀)能力,其生物学行为与有高度侵蚀性的肿瘤细胞相似, Hypertensive disorder in pregnancy is one of the major causes of morbidity and mortality in pregnant women and perinatals, and its etiology is not yet known. In recent years, the study of hypertensive disorders in pregnancy found that trophoblast cells on the erosion of the endometrium is the main reason for the disease [1]. The physiological functions of trophoblasts include the ability to proliferate, differentiate, and prolong (erode), their biological behavior is similar to that of highly aggressive tumor cells,