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目的 :观察肝病治疗仪及甘利欣注射液和中药联合治疗慢性乙型肝炎的疗效。方法 :治疗组 84例慢性乙型肝炎患者应用肝病治疗仪治疗 ,每日 1次 ,每次 30分钟 ;甘利欣注射液 15 0~ 2 0 0 mg加 10 %葡萄糖2 5 0 ml静滴 ;另用中药汤剂口服 ,每日 1剂 ;14日为 1个疗程 ,连用 2个疗程。对照组 84例采用西药治疗。观察临床症状、肝脾回缩情况、肝功能及 HBe Ag等指标。结果 :治疗组显效率为 73.8% ,总有效率为 10 0 .0 % ;对照组显效率为 44 .0 % ,总有效率为 79.8% ,2组比较均有显著性差异 (P均 <0 .0 1)。 HBe Ag阴转率治疗组为5 4.8% ,对照组为 2 2 .6 % ;治疗组治疗后血清中总胆红素〔(16 .12± 6 .41)μm ol/L〕、丙氨酸转氨酶〔(4 2 .10±13.91) U〕和对照组治疗后血清中总胆红素〔(30 .78± 10 .2 9)μm ol/L〕、丙氨酸转氨酶〔(79.18± 19.19) U〕均明显下降 (P均 <0 .0 5 )。结论 :肝病治疗仪及甘利欣注射液合中药联合治疗慢性乙型肝炎 ,在改善临床表现、肝功能和病毒学指标等方面疗效显著 ,优于单纯西药治疗
Objective: To observe the curative effect of liver disease treatment instrument and Gan Lixin injection and traditional Chinese medicine in the treatment of chronic hepatitis B. Methods: The treatment group of 84 patients with chronic hepatitis B treatment of liver disease treatment device, once daily for 30 minutes; Glycyrrhizin injection 150 ~ 200 mg plus 10% glucose 250 ml intravenous infusion; the other With traditional Chinese medicine decoction oral, daily 1; 14 for a course of treatment, once every 2 courses. The control group of 84 patients treated with western medicine. Observation of clinical symptoms, liver and spleen retraction, liver function and HBeAg and other indicators. Results: The effective rate of the treatment group was 73.8%, the total effective rate was 100.0%; the effective rate of the control group was 44.0%, the total effective rate was 79.8%, there were significant differences between the two groups (all P <0 .0 1). In the treatment group, total bilirubin [(16.12 ± 6.14) μmol / L], alanine Serum levels of total bilirubin 〔(30.78 ± 10.29) μmol / L〕, alanine aminotransferase 〔〔(79.18 ± 19.19)〕, aminotransferase 〔(42.10 ± 13.91〕 U〕 and control group U〕 were significantly decreased (P <0.05). Conclusion: The treatment of liver disease and Gan Lixin injection combined with traditional Chinese medicine treatment of chronic hepatitis B, in improving clinical manifestations, liver function and virological indicators such as significant effect, superior to Western medicine alone