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目的观察治疗胃食管反流性哮喘的疗效。方法将46例分为两组:治疗组23例应用糖皮质激素和β2受体激动剂吸入平喘,加用胃动力药多潘立酮10mg口服,3次/d,H2受体阻滞剂雷尼替丁0.15g口服,2次/d,疗程1周。对照组23例应用糖皮质激素和β2受体激动剂吸入平喘治疗,疗程1周。结果治疗组有效率87%,对照组有效率52%,两组差异P<0.05。结论哮喘与GERD之间关系密切,抗哮喘的同时应注意抗胃食管反流治疗,对哮喘发作起重要作用。
Objective To observe the therapeutic effect of gastroesophageal reflux disease on asthma. Methods 46 cases were divided into two groups: the treatment group, 23 cases of glucocorticoid and β2 receptor agonist inhalation and asthma, plus gastric motility drug domperidone 10mg orally, 3 times / d, H2 receptor blocker ranitidine Ding 0.15g orally, 2 times / d, treatment for 1 week. Control group, 23 cases of glucocorticoid and β2 receptor agonist inhalation asthma treatment, treatment for 1 week. Results The effective rate was 87% in the treatment group and 52% in the control group, with a significant difference between the two groups (P <0.05). Conclusion There is a close relationship between asthma and GERD. Anti-asthma and anti-gastroesophageal reflux therapy should be noted, which plays an important role in asthma attacks.