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活性氧在细胞氧化磷酸化过程及白细胞杀菌或受某些刺激等情况下经常产生。近年来国内外报道白细胞活性氧产生能不但与细胞杀菌功能有关,还与组织损伤、老化及细胞凋亡有关。但目前尚未见到有关活性氧产生能在细菌及病毒感染时变化的报道。为探讨活性氧在急性感染中的变化,我们用流式细胞仪(FCM)检测了急性细菌及病毒感染患儿各20例末梢血中的中性粒细胞(PMN)活性氧产生能,现报道如下。
Reactive oxygen species often occur in the process of cellular oxidative phosphorylation and leukocyte sterilization or by some stimulus. In recent years, domestic and foreign reports of white blood cell reactive oxygen species can not only function with cell sterilization, but also with tissue damage, aging and apoptosis. However, there is no report on the change of active oxygen production during bacterial and viral infections. To investigate the changes of reactive oxygen species (ROS) in acute infections, we used flow cytometry (FCM) to detect the production of reactive oxygen species of neutrophils (PMN) in peripheral blood of 20 children with acute bacterial and viral infections. as follows.