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目的:探讨失眠症患者采用超低频经颅磁刺激联合护理干预临床疗效。方法:将温州市第七人民医院2015年1月-2016年12月收治的60例失眠症患者按照随机数字表法分为对照组(酒石酸唑吡坦5~10mg)与治疗组(酒石酸唑吡坦+超低频经颅磁刺激联合护理干预),各30例。分别于治疗前、治疗4周后评价患者睡眠及不良情绪情况,记录两组临床疗效及不良反应。结果:治疗组治疗4周后匹茨堡睡眠质量指数(PSQI)总分、睡眠质量、睡眠时间、入睡时间、睡眠障碍、睡眠效率、催眠药物及日间功能障碍评分均明显低于对照组,两组患者各项指标评分均明显低于治疗前,P<0.05。治疗组治疗总有效率90.0%,明显高于对照组60.0%,χ~2=7.20,P=0.02;治疗组治疗4周后HAMA、HAMD评分分别为(10.25±6.75)分、(12.74±5.61)分,明显低于对照组(21.36±6.42)分、(16.79±8.71)分,t=(6.53,2.14),P=(0.00,0.03);两组治疗4周后HAMA、HAMD评分明显低于治疗前,P<0.05。治疗组不良反应率6.67%与对照组10.0%比较,χ~2=0.21,P=0.64。结论:超低频经颅磁刺激联合护理干预治疗失眠症患者可有助于改善其睡眠状况及不良情绪,提高临床疗效,且不会增加不良反应,值得推广。
Objective: To investigate the clinical effect of ultra-low frequency transcranial magnetic stimulation combined with nursing intervention in patients with insomnia. Methods: Sixty insomnia patients admitted to Wenzhou No.7 People’s Hospital from January 2015 to December 2016 were randomly divided into control group (Zolpidem 5-100 mg) and treatment group (Zolpidem tartrate Tan + ultra-low frequency transcranial magnetic stimulation combined with nursing intervention), each 30 cases. Respectively before treatment, after 4 weeks of treatment evaluation of patients with sleep and adverse emotions, the two groups were recorded clinical efficacy and adverse reactions. Results: The scores of Pittsburgh Sleep Quality Index (PSQI), sleep quality, sleep time, sleep time, sleep disturbance, sleep efficiency, hypnotic drugs and daytime dysfunction scores of the treatment group were significantly lower than those of the control group after 4 weeks of treatment, The score of each index in both groups was significantly lower than before treatment, P <0.05. The total effective rate of treatment group was 90.0%, significantly higher than that of control group 60.0%, χ ~ 2 = 7.20, P = 0.02. The HAMA and HAMD scores of the treatment group were (10.25 ± 6.75), (12.74 ± 5.61) ) Was significantly lower than that of the control group (21.36 ± 6.42), (16.79 ± 8.71), t = (6.53,2.14), P = (0.00,0.03); HAMA and HAMD scores were significantly lower in both groups after 4 weeks of treatment Before treatment, P <0.05. Adverse reaction rate in treatment group was 6.67% compared with 10.0% in control group, χ ~ 2 = 0.21, P = 0.64. Conclusion: Ultra-low frequency transcranial magnetic stimulation combined with nursing intervention in patients with insomnia can help to improve their sleep conditions and adverse emotions, improve clinical efficacy, and does not increase adverse reactions, it is worth promoting.