目的：探讨医学院学生的自杀意念与希望特质和抑郁情绪的关系，以及在其中希望特质的调节作用。方法：选择某医学院各年级学生按比例进行分层整群随机抽样调查，发放自杀意念自评量表（SIOSS）、希望特质量表（DHS）和抑郁自评量表（SDS）。回收有效问卷148份。结果：样本中自杀意念检出率为81．％，其中有自杀意念组抑郁得分高于无自杀意念组（t＝86．99，P＜00．01），希望特质评分低于无自杀意念组（t＝‐60．77，P＜00．01）；抑郁得分与自杀意念得分成正相关（t＝06．81，P＜00．1），希望特质得分与自杀意念得分成负相关（t＝‐03．28，P＜00．1）。并且分层回归显示，抑郁自评量表得分与希望特质的交互作用显著（ t＝‐47．27，P＜00．1），即希望特质在抑郁情绪与自杀意念之间有显著的调节作用。结论：自杀意念与抑郁情绪消极相关，与希望特质积极相关。关注大学生抑郁情绪，提高大学生希望特质水平，可以增强危机因素的抵抗作用，有助于对大学生自杀危机干预工作提供科学参考。“,”Objective:To explore the relationship among suicidal ideation ,dis-positional hope and depression emo‐tion in medical college students ,especially ,the mediating effect of dis-positional hope .Methods:Surveying the medi‐cal students collected by cluster randomized sampling method and distributing questionnaire as Self -rating Idea of Suicide Scale(SIOSS) ,Dis -positional Hope Scale(DHS) ,and Self -rating Depression Scale(SDS) .at last ,there were 148 effective questionnaire .Results:8 1.% students had suicidal idea ,the score of SDS was higher in students with suicidal idea(t=8 6.99 ,P<0 0.01)and the score of DHS was higher in students without suicidal idea(t=‐6 0.77 , P<0 0.01) .We also found positive correlation between the score of depression and the score of suicidal ideation(r=0 6.81 ,P<0 0.1) ,and negative correlation between the score of dis-positional hope and suicidal ideation .(r=‐0 3.28 , P<0 0.1) .And hierarchical regression analysis showed that the score of SDS and SIOSS had significantly interactive effects I.t meant that the dis-positional hope acted as a significant moderator between depression emotion and sui‐cidal ideation .Conclusion:There are negative correlation between dis-positional hope and suicidal ideation ,but posi‐tive correlation between depression and suicidal ideation S.o we should pay attention to depressive emotion of college students ,and enhance theirs hope dis-positional as protective effect to mental healthy crisis .The survey aims to pro‐vide a scientific reference for college students suicide crisis intervention work .