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CD４４分子是一种跨膜糖蛋白，是细胞粘附因子之一。因其介导着肿瘤细胞与宿主细胞分子和细胞外基质的相互作用，而成为研究肿瘤转移及预后的热点。其中的含有外显因子v６的CD４４变异体（CD４４v６）与肿瘤的关系较密切犤１，２犦，而且它在人类肿瘤的侵袭和转移的过程中均起
CD44 molecule is a transmembrane glycoprotein, one of the cell adhesion factors. Because of its mediated tumor cell and host cell molecules and extracellular matrix interactions, and become a research focus on tumor metastasis and prognosis. Among them, the CD44 variant (CD44v6) containing the exogenous factor v6 has a close relationship with the tumor, and it plays an important role in the invasion and metastasis of human tumors