Hepatocellular-cholangiocarcinoma with sarcomatous change: Clinicopathological features and outcomes

来源 :国际肝胆胰疾病杂志(英文版) | 被引量 : 0次 | 上传用户:luck88
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Combined hepatocellular-cholangiocarcinoma (cHCC-CCA) is a rare type of cancer, accounting for 0.4%–14.2% of hepato-carcinoma. Hepatic sarcoma is only less than 2% of primary malignant liver tu- mors. Thus, sarcomatoid cHCC-CCA is extremely rare. To the best of our knowledge, only twenty-six cases had been reported in the lit- erature [ 1 –19 ]. Consensus cannot be reached due to the difficulty of preoperative pathological diagnosis and disagreement for the se- lection of the treatment. Therefore, clinicopathological features and outcome data about sarcomatoid cHCC-CCA are essential for diag- nosis and treatment. We reported in this article three cases with clinical data and prognostic analysis, and summarized 26 cases of sarcomatoid cHCC-CCA from published literatures.
其他文献
高风险的入境航班及相关区域是我国当前新冠病毒肺炎病例输入的主要关口,入境航班及相关场所的医疗保障存在缺乏大医疗环境支撑、感染不确定性、现场救治决策难、潜在暴露感染风险、器材设施设备消杀困难、关联单位多、协调难度大等特点和风险点.原则上宜建立区域医疗保障机制,专人、专车、专用设施设备,医护人员要集中居住、做好自身防护措施,在让患者得到高效医疗救治的同时,又要规避医疗事件可能造成的疫情播散.入境航班及相关工作区域的病例,宜充分利用区域负压隔离舱等设施设备,原则上应通过视频远程初步了解病情,如患者病情平缓,应尽
Background: Treatment of hepatocellular carcinoma (HCC) is challenging as most patients are diagnosed at advanced stage with underlying chronic liver conditions. Conventional systemic chemotherapy has failed in HCC, and the clinical efficacy of FDA-approv
Background: Hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF) has a high short-term mortality. However, the treatment progression for HBV-ACLF in China in the past decade has not been well characterized. The present study aimed to determ
自2019-12新型冠状病毒肺炎(Coronavirus Disease 2019,COVID-19)爆发以来,因其人群普遍易感、潜伏期长、临床重症患者多等特点,给全国人民生产生活产生巨大影响.因疑似患者数量多,且需要单人单间隔离,在传染病病房严重不足的情况下,多地的医院在原有普通病房基础之上,进行紧急快速改造,成立应急病区来收治患者.自2020-01-01至2020-03-31,我院急诊科成立应急病区后,共收治疑似新冠患者61例,其中新冠阳性确诊患者12例,医护人员感染为零,院内感染为零.本文从应急病区
Background: The sterile inflammatory response is one of the key mechanisms leading to hepatic ischemia-reperfusion injury. Melatonin has been shown to prevent organ injuries, but its roles in the inflammatory response after hepatic ischemia-reperfusion in
Background: To date, there is controversy regarding unilateral versus bilateral stent placement in patients with malignant hilar biliary strictures (MHBSs). The aim of this study was to compare the clinical out- comes and complications of unilateral and b
Background: Hepatitis C virus (HCV) infection is a worldwide issue. However, the current treatment for hepatitis C has many shortcomings. Toll-like receptors (TLRs) are pattern recognition receptors involved in HCV infection, and an increasing number of s
Choledochal cysts (CCs), first described by Vater and Ezler in 1723, are rare congenital cystic dilations of biliary tract [1] . The most widely adopted classification system from Todani et al. di- vides CCs into five major types and several subtypes [2]
期刊
Background: Hepatectomy in patients with large tumor load may result in postoperative liver failure and associated complications due to excessive liver parenchyma removal. Conventional two-stage hep- atectomy (TSH) and associating liver partition and port
Glycogen storage disease type I (GSD type I), also known as von Gierke disease, is an autosomal recessive disorder of the glycogen metabolism pathway, caused by a deficiency of glucose- 6-phosphatase (GSD type Ia) or glucose-6-phosphate translocase (GSD t
期刊