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目的 :探讨晚发型维生素K缺乏性出血的临床特点。方法 :回顾性分析 86例晚发型维生素K缺乏性出血病人的临床资料。结果 :全组病例中 76例 ( 88% )为纯母乳喂养儿 ,病前有前驱感染并用过抗生素者 2 8例 ,皮下出血或注射部位出血不止者 3 6例( 4 1.4% ) ,消化道出血 40例 ( 4 6.5 % ) ,颅内出血 62例 ( 72 % )。均有不同程度贫血。 78例查凝血酶原时间 (PT )延长。入院时误诊或漏诊 18例。结论 :晚发型维生素K缺乏性出血临床表现复杂 ,尤其颅内出血的临床症状不典型 ,易造成误诊及漏诊 ,应加深对该病的认识。
Objective: To investigate the clinical features of late onset vitamin K deficiency bleeding. Methods: The clinical data of 86 patients with late onset vitamin K deficiency bleeding were retrospectively analyzed. RESULTS: Totally 76 breastfeeding children (88%) were exclusively breastfeeding, 28 were infected with prodromal infection and had used antibiotics, 36 (4.14%) had subcutaneous hemorrhage or bleeding at the injection site, Bleeding in 40 cases (4 6.5%), intracranial hemorrhage in 62 cases (72%). Have varying degrees of anemia. 78 cases to check prothrombin time (PT) extended. 18 cases were misdiagnosed or missed on admission. Conclusions: The clinical manifestations of late onset vitamin K deficiency bleeding are complex, especially the clinical symptoms of intracranial hemorrhage are not typical, which may lead to misdiagnosis and missed diagnosis. The understanding of this disease should be deepened.