目的探讨血液灌流(HP)串联血液透析(HD)对尿毒症患者的毒素清除与症状改善是否优于单纯血液透析。方法维持性透析患者36例,分为串联组与单纯血透组,每组各18例,串联组每2周1次HP+HD,其余与单纯透析组相同。结果串联组在毒素清除与临床症状改善方面均优于对照组。结论串联组能够更加充分的清除尿毒症毒素,更加明显的改善患者临床症状,值得在临床中应用推广。 Objective To investigate if hemoperfusion and symptom improvement of hemodialysis (HP) tandem hemodialysis (HD) in patients with uremia is better than that of hemodialysis alone. Methods Thirty-six patients with maintenance hemodialysis were divided into series group and simple hemodialysis group, with 18 cases in each group. HP + HD was given every two weeks in series group, and the rest were the same as dialysis group. Results The tandem group was better than the control group in removing toxins and improving clinical symptoms. Conclusions The tandem group can more fully remove uremic toxins, and more obviously improve the clinical symptoms of patients, it is worth in the clinical application.