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在心血管疾病的治疗中,心肌组织的再生修复及其过程中面临的心肌纤维化是心血管疾病的发生与发展的关键。结缔组织生长因子作为一种成纤维细胞生长因子,在心肌组织纤维化的发生和发展过程中起着重要作用,因此,针对结缔组织生长因子在心血管疾病中作用的研究也陆续展开,结缔组织生长因子有望成为心血管疾病中抗纤维化心肌保护治疗的新靶点。
In the treatment of cardiovascular diseases, myocardial tissue regeneration and repair and the process of myocardial fibrosis is the key to the occurrence and development of cardiovascular diseases. As a fibroblast growth factor, connective tissue growth factor plays an important role in the occurrence and development of myocardial fibrosis. Therefore, studies on the role of connective tissue growth factor in cardiovascular diseases have also been carried out successively. The growth of connective tissue Factor is expected to become a new target for the treatment of anti-fibrotic myocardial protection in cardiovascular disease.