论文部分内容阅读
肝细胞癌的自发性破裂是一威胁生命的情况,在日本约10％肝癌病人因之死亡,在亚非肝癌高发地区约12％～14.5％肝癌病例发生这一并发症。其发生机制不甚清楚,首先可能由于肿瘤侵犯而致肝静脉阻塞,在肝硬变伴门静脉高压以及肿瘤浸润以致不能经门静脉回流等情况下,发生肿瘤内静脉充血,加上轻微创伤、凝血病和肿瘤中心坏死等因素使肝癌组织内出血,一旦有肿瘤突然增大和压力增高,就可发生破裂和引起血腹。口服避孕药和动脉栓塞疗法（TAE）的影响不肯定。
The spontaneous rupture of hepatocellular carcinoma is a life-threatening condition. About 10% of liver cancer patients in Japan die because of this complication. This complication occurs in about 12% to 14.5% of liver cancer cases in high-risk areas in Asia and Africa. The mechanism of its occurrence is not clear. Firstly, hepatic vein obstruction may be caused by tumor invasion. Intravenous hyperemia occurs in patients with hepatic cirrhosis associated with portal hypertension and infiltration of the tumor so as not to pass through the portal vein, combined with minor trauma and coagulopathy. And tumor necrosis and other factors make the hepatocarcinoma tissue hemorrhage. Once the tumor suddenly increases and the pressure increases, rupture and hemorrhage may occur. The effects of oral contraceptives and arterial embolization therapy (TAE) are uncertain.