论文部分内容阅读
目的有卵巢子宫内膜异位囊肿的女性发生卵巢透明细胞癌和子宫内膜样腺癌的几率远大于没有的女性。本研究拟探讨卵巢子宫内膜异位囊肿恶变的相关危险因素,为临床的预防提供依据。方法回顾性分析2010-06-30-2015-12-31江苏省苏北人民医院收治的17例卵巢子宫内膜异位囊肿恶变患者(病例组)及51例良性卵巢子宫内膜异位囊肿患者(对照组)的临床资料,采用χ~2检验和Logistic回归分析探讨卵巢子宫内膜异位囊肿恶变的危险因素。结果单因素分析显示,年龄(P<0.001)、囊肿直径(P=0.03)、绝经与否(P=0.006)、囊肿有乳头(P<0.001)等因素和卵巢子宫内膜异位囊肿恶变相关。多因素Logistic回归分析显示,年龄≥49岁(OR=1.92,P<0.05)、绝经(OR=3.09,P<0.001)、囊肿直径≥11cm(OR=2.68,P<0.05)、囊壁有乳头(OR=3.63,P<0.05)为卵巢子宫内膜异位囊肿恶变的危险因素。结论年龄≥49岁、已绝经、囊壁有乳头、囊肿直径≥11cm是卵巢子宫内膜异位囊肿恶变的独立危险因素,该类患者囊肿恶变风险增大,应予以积极的干预治疗。
The purpose of women with ovarian endometriosis Ovarian clear cell carcinoma and endometrial adenocarcinoma is far more likely than no women. This study was to explore the risk factors associated with malignant transformation of ovarian endometriotic cysts, providing the basis for clinical prevention. Methods A retrospective analysis of 17 patients with malignant ovarian endometriosis (case group) and 51 patients with benign ovarian endometriosis (SUH) treated in Jiangsu Provincial People’s Hospital of North Jiangsu Province 2010-06-30-2015-12-31 (Control group). The χ ~ 2 test and Logistic regression analysis were used to explore the risk factors of ovarian endometriosis. Results Univariate analysis showed that age (P <0.001), cyst diameter (P = 0.03), menopause (P = 0.006), cyst nipples (P <0.001) and other malignancies of ovarian endometriosis . Multivariate Logistic regression analysis showed that the age of the patients was 49 years or older (OR = 1.92, P <0.05), the diameter of the cyst was ≥11 cm (OR = 2.68, P <0.05) (OR = 3.63, P <0.05) were the risk factors of malignant ovarian endometriosis. Conclusions Age ≥ 49 years old, menopause, wall nipple, cyst diameter ≥ 11cm is an independent risk factor for ovarian endometriosis, malignant transformation of cyst in such patients increased risk should be positive intervention.