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观察益气温阳护卫汤对哮喘豚鼠外周血白细胞糖皮质激素受体 (GCR)特异性结合位点的影响。结果 :哮喘组外周血白细胞GCR水平明显降低 ;地塞米松组最低 ,与其他各组比较有显著性差异 (P <0 0 5 )。益气温阳护卫汤不同剂量组均能提高GCR特异性结合位点。结论 :益气温阳护卫汤可以提高GCR特异性结合位点 ,能安全有效地用于哮喘防治
Objective To observe the effect of Yiwen Yangyang Huwei Decoction on the specific binding sites of glucocorticoid receptor (GCR) in leukocytes of asthmatic guinea pigs. RESULTS: GCR levels in peripheral blood leukocytes were significantly decreased in the asthma group, and the dexamethasone group was the lowest, with a significant difference from other groups (P < 0.05). Yiqi Wenyang Huwei Tang can increase the specific binding site of GCR in different dosage groups. Conclusion :Yiwen Yangyang Huwei Decoction can increase the specific binding site of GCR and can be used safely and effectively in the prevention and treatment of asthma.