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目的观察干扰素栓联合激光治疗宫颈糜烂的疗效和作用机理。方法用干扰素栓联合激光治疗宫颈糜烂92例,术前用药2个疗程,术后用药1～2疗程,同时与79例单用干扰素栓和83例单用激光作对比。结果治疗组痊愈率97.83％,对照组分别为25.32％和43.49％,两组比较有非常显著性差异(P<0.005,P<0.005)。治疗组不良反应明显低于对照组,创面愈合时间与对照组比较有显著性差异(P<0.005)。结论干扰素栓联合激光治疗宫颈糜烂能提高治愈率,减少不良反应,加速创面愈合。
Objective To observe the efficacy and mechanism of interferon suppository combined with laser treatment of cervical erosion. Methods 92 cases of cervical erosion treated with interferon suppository and laser were treated with 2 courses of preoperative medication and 1 ~ 2 courses of treatment after operation. Meanwhile, they were compared with 79 cases of single interferon suppository and 83 cases of single laser. Results The cure rate was 97.83% in the treatment group and 25.32% in the control group and 43.49% in the control group, respectively. There was a significant difference between the two groups (P <0.005, P <0.005). Adverse reactions in the treatment group were significantly lower than those in the control group, and wound healing time was significantly different from the control group (P <0.005). Conclusion Interferon plug combined with laser treatment of cervical erosion can improve the cure rate, reduce adverse reactions and accelerate wound healing.