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在568名HBsAg携带者的肝活检标本中,采用免疫荧光染色发现137名δ抗原阳性,其中男111名,女26名,21—40岁居多。组织学和免疫荧光特点:137名肝内存在δ抗原者,组织学检查均为慢性肝炎。其中6名(4%)为慢性小叶性肝炎(CLH);6名慢性迁延性肝炎(CPH);93名(70%)慢性活动性肝炎(CAH);30名(20%)CAH伴肝硬化,其中2名非活动性肝炎中有1名伴肝细胞癌。在肝细胞核内见到有δ抗原的标本124份,在核和胞浆同时见到者9份,仅在胞浆见到者有4份。非活动性肝硬化患者可见δ荧光分散存在,CAH伴肝硬化患者比较多些
Of the 568 HBsAg-positive liver biopsy specimens, 137 were positive for δ antigen using immunofluorescence staining, including 111 males and 26 females, mostly from 21 to 40 years old. Histology and immunofluorescence characteristics: There are 137 patients with δ antigen, histological examination are chronic hepatitis. 6 (4%) had chronic lobular hepatitis (CLH); 6 chronic persistent hepatitis (CPH); 93 (70%) chronic active hepatitis (CAH); 30 (20%) CAH with cirrhosis , Of which one in two inactive hepatitis with hepatocellular carcinoma. In the nucleus of hepatocytes, there were 124 specimens with δ antigen, 9 in the nucleus and cytoplasm, and 4 in cytoplasm only. In patients with non-active cirrhosis seen δ fluorescence dispersion exists, CAH patients with cirrhosis more