目的:观察运用温阳活血化湿法治疗胆道闭锁术后患儿的临床疗效,并从肝功能方面来探讨其治疗的机制。方法:纳入胆道闭锁的手术患儿23例。随机分为治疗组与对照组,治疗组9例予温阳活血化湿法结合西药治疗,对照组14例单用西药治疗,总结术前及治疗后4周患儿的证候积分;并对治疗前后的肝功能进行记录。结果:治疗4周后,治疗组患儿均完成研究治疗,对照组12例完成研究治疗。对照组总有效率为25.0%,治疗组总有效率为77.8%,治疗组疗效优于对照组(P<0.05);治疗组症状改善情况优于对照组;治疗组胁下肿块性质、腹胀及食欲等症状改善方面明显优于对照组;两组治疗后ALT、AST、ALP、TB、DB及IB均较治疗前减低;治疗前后差值比较,治疗组ALT、AST、ALP、TB、DB及IB均差值均高于对照组。结论:在西医基础上加用温阳活血化湿法治疗可改善胆道闭锁术后患儿的胁下肿块性质、腹胀及食欲等症状体征,可改善肝功能指标(ALT、AST、ALP、TB、DB、IB)。 Objective: To observe the clinical efficacy of warming Yang and promoting blood circulation and removing dampness in the treatment of children with biliary atresia, and to explore the mechanism of its treatment from the aspect of liver function. Methods: Twenty-three children with biliary atresia were included. Nine cases were randomly divided into treatment group and control group. The treatment group was treated with warming Yang, promoting blood circulation and dampness combined with western medicine. In the control group, 14 cases were treated with western medicine alone, and the scores of syndromes were preoperatively and 4 weeks after treatment. Liver function before and after treatment was recorded. Results: After 4 weeks of treatment, all the children in the treatment group completed the study and the control group of 12 patients completed the study and treatment. The total effective rate of the control group was 25.0%, the total effective rate of the treatment group was 77.8%, and the curative effect of the treatment group was better than that of the control group (P <0.05); the symptom improvement of the treatment group was better than that of the control group; ALT, AST, ALP, TB, DB and IB were lower than before treatment in both groups after treatment; differences in ALT, AST, ALP, TB, DB, IB difference were higher than the control group. Conclusion: The treatment of warming Yang and promoting blood circulation and removing dampness on the basis of western medicine can improve the symptoms of bulimia, abdominal distension and appetite in children after biliary atresia, and can improve the indexes of liver function (ALT, AST, ALP, TB, DB, IB).