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以成人桥本氏病60例为对照,分析了60例儿童桥本氏病。显示:①阳性的自身免疫甲状腺病家族史较成人组多见(P=0.0126);②甲状腺峡部大为主者多于成人组(X2=49,P<0.05);甲状腺质地硬或韧如橡皮者显著少于成人组(X2=12.48,P<0.001),伴结节者显著少于成人组(X2=8.2,P<0.01);③甲状腺球蛋白抗体(TGAb)和微粒体抗体(TMAb)阴性者显著多于成人组(X2=5.1和X3=5.81,P均<0.05);④淋巴细胞型显著多于成人组(X2=7.01,P<0.01),而嗜酸细胞型明显少于成人组(X3=3.89,P<0.05);⑤甲状腺肿大程度、生化和碘代谢,两组相比差异无显著性(P>0.05)。
60 adult Hashimoto’s disease as a control, analysis of 60 cases of Hashimoto’s disease in children. The results showed that: (1) The family history of positive autoimmune thyroid disease was more common than that of adult group (P = 0.0126); ② The predominance of thyroid isthmus was more than that of adult group (X2 = 49, P <0.05) (X2 = 8.2, P <0.01); ③ Thyroglobulin antibody (TGAb) was significantly lower than that of the adult group (X2 = 8.28, P < The number of TMAb was significantly more than that of the adult group (χ2 = 5.1 and X3 = 5.81, P <0.05). ④ The lymphocyte types were significantly more than those in the adult group (X2 = 7.01, P < 0.01), while eosinophilic cell type was significantly less than that of adult group (X3 = 3.89, P <0.05); ⑤The degree of goiter, biochemical and iodine metabolism were not significantly different between the two groups > 0.05).