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1989年10月至1996年10月,采用胸腺切除术治疗各型重症肌无力43例,其中胸腺瘤28例(恶性9例),胸腺增生14例,胸腺正常1例。术后早期死亡2例,死亡率4.65%,治愈41例。37例随访3月至6年零9月,结果满意,症状完全缓解16例,改善18例,无变化2例。死亡1例。病情严重者于胸腺切除术后早期行气管切开术,短期应用较大剂量糖皮质激素是防治术后重症肌无力危象的有效措施。胸腺肿瘤已侵及包膜或有局限性恶变者,术后放疗可以减少复发率、延长生存时间。
From October 1989 to October 1996, 43 patients with various types of myasthenia gravis were treated with thymectomy, including 28 cases of thymoma (9 cases of malignancy), 14 cases of thymus hyperplasia and 1 case of normal thymus. Two patients died early in the postoperative period, with a mortality rate of 4.65% and 41 cases were cured. 37 cases were followed up for 3 months to 6 years and 0 months. The results were satisfactory, symptoms were completely relieved in 16 cases, improvement in 18 cases, no change in 2 cases. 1 case of death. Serious cases of tracheotomy in the early post-thymectomy, short-term use of larger doses of glucocorticoid is an effective measure to prevent and treat postoperative myasthenia gravis crisis. Thymus tumor has been invading the envelope or the limitations of malignant transformation, postoperative radiotherapy can reduce the recurrence rate and prolong survival time.