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目的了解急性有机磷农药中毒后患者血小板与T淋巴细胞动态变化情况以指导临床诊断治疗。方法对来我院就诊的有机磷农药中毒患者分时段抽取静脉血检测生理、生化指标及免疫功能指标,并与对照组比较。结果中毒后T淋巴细胞亚群明显下降,血小板参数异常较对照组有明显差异。结论急性有机磷农药中毒后患者细胞免疫功能受损,易合并感染。血小板各参数变化对预后不具有重要影响,但可了解中毒程度、了解病情、指导治疗。
Objective To understand the dynamic changes of platelets and T lymphocytes in patients with acute organophosphorus pesticide poisoning to guide the clinical diagnosis and treatment. Methods The patients with organophosphorus pesticide poisoning who came to our hospital were drawn venous blood to examine the physiological, biochemical and immune function indexes at different time points and compared with the control group. Results T-lymphocyte subpopulation was significantly decreased after poisoning, abnormal platelet parameters than the control group were significantly different. Conclusion Acute organophosphorus pesticide poisoning patients with impaired cellular immunity, easy to co-infection. Changes in platelet parameters have no important effect on prognosis, but can understand the degree of poisoning, to understand the condition, guide the treatment.