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目的探讨血清a-L-岩藻糖苷酶(AFU)和甲胎蛋白(AFP)联合检测对原发性肝癌诊断的临床价值。方法对65例原发性肝癌和30例正常体检者血清AFU和AFP同步测定并进行对照。结果原发性肝癌患者血清AFU和AFP水平及阳性率均明显高于正常对照组(P<0.001);联合检测的敏感性和诊断准确性均比单项检测高。结论联合检测血清中的AFU和AFP对原发性肝癌的诊断具有重要临床价值。
Objective To investigate the clinical value of serum a-L-fucosidase (AFU) and alpha fetoprotein (AFP) in the diagnosis of primary liver cancer. Methods Serum AFU and AFP were detected in 65 cases of primary hepatocellular carcinoma and 30 cases of normal controls and compared. Results The serum levels of AFU and AFP in patients with primary liver cancer were significantly higher than those in the normal control group (P <0.001). The sensitivity and diagnostic accuracy of the combined detection were higher than those of the single test. Conclusion The combined detection of serum AFU and AFP has important clinical value in the diagnosis of primary liver cancer.