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目的了解胆红素对红细胞免疫功能的影响。方法对 ３８例黄疸患儿进行胆红素和红细胞免疫功能检测，红细胞Ｃ３ｂ补体受体花环（ＲＢＣ－Ｃ３ｂＲＲ）和红细胞兔疫复合物受体花环（ＲＢＣ－ＩＣＲ）采用酵母多糖花环试验，血清胆红素采用苯甲酸尿素比色法。结果发现该组患儿ＲＢＣ－Ｃ３ｂＲＲ，红细胞辅助因子（ＲＩＥＲ）明显降低，而ＲＢＣ—ＩＣＲ，红细胞抑制因子（ＲＩＦＲ）明显升高，并发现ＲＢＣ—Ｃ３ｂＲＲ，ＲＩＥＲ与胆红素浓度呈负相关，ＲＢＣ－ＩＣＲ，ＲＩＦＲ与胆红素浓度呈正相关。结论血清胆红素能引起继发性红细胞免疫功能低下。
Objective To understand the impact of bilirubin on erythrocyte immune function. Methods Immunity of bilirubin and erythrocyte were detected in 38 children with jaundice. The RBC-C3bRR and the RBC-ICR of erythrocytes were assayed by yeast polysaccharide wreath, Benzoic acid urea colorimetry. The results showed that the RBC-C3bRR and RIER were significantly decreased and the RBC-ICR and erythrocyte inhibitory factor (RIFR) were significantly increased in this group. The RBC-C3bRR and RIER were negatively correlated with the concentration of bilirubin, RBC-ICR, RIFR and bilirubin concentration was positively correlated. Conclusion Serum bilirubin can cause secondary erythrocyte immune dysfunction.