The paper investigated the texture evolution of a biomedical β-titanium alloy (Ti-28Nb-13Zr-2Fe) under 15%-85% cold rolling reduction and 700°C-900°C recrystallization annealing treatment,and clarified the effects of crystal orientation on Young’s modulus of the alloy.Orientation distribution function (ODF) maps and electron backscatter diffraction (EBSD) analysis revealed that the rolling texture type changed with the increase of reduction according to the sequence:α-fiber texture→γ-fiber texture→α-rotated cubic texture.Young’s modulus exhibited the lowest value 54 GPa under 15% reduction.Strong {111}<112> γ-fiber texture was developed after rolling 85% reduction and annealing at 700°C,which was favorable to decreasing Young’s modulus in comparison with randomly orientated microstructure.Cyclic loading-unloading tensile test proved that the gradual rotation of {110} slip plane during plastic deformation promoted the development of {001}<110> texture component,leading to the marked decrease of Young’s modulus. The paper investigated the texture evolution of a biomedical β-titanium alloy (Ti-28Nb-13Zr-2Fe) under 15% -85% cold rolling reduction and 700 ° C-900 ° C recrystallization annealing treatment, and clarified the effects of crystal orientation on Young’s modulus of the alloy. Organization distribution function (ODF) maps and electron backscatter diffraction (EBSD) analysis revealed that the rolling texture type changed with the increase of reduction according to the sequence: α-fiber texture → γ-fiber texture → α -rotated cubic texture. Your modulus exhibited the lowest value 54 GPa under 15% reduction. Strong {111} <112> γ-fiber texture was developed after rolling 85% reduction and annealing at 700 ° C, which was favorable to decreasing Young’s modulus in comparison with randomly orientated microstructure. Cyclic loading-unloading tensile test proved that the gradual rotation of {110} slip plane during plastic deformation promoted the development of {001} <110> texture component, leading to th e marked decrease of Young’s modulus.