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肥胖可以引起一系列生理功能紊乱,如高血压、动脉粥样硬化、胰岛素抵抗、高脂血症和肾功能障碍等。原发性高血压的发生60%~70%可归因于肥胖。早在20世纪60年代,Framingham心脏研究就发现,体重每增加4.5 kg,收缩压就会上升4 mm Hg,肥胖可以增加高血压的患病风险。肥胖与高血压并存,可以增加血压控制的难度,促进多重心血管代谢危险因素聚集,增加心脑血管疾病风险[1]。近年来,高血压与肥胖的患病率
Obesity can cause a number of physiological disorders, such as hypertension, atherosclerosis, insulin resistance, hyperlipidemia and renal dysfunction. The incidence of essential hypertension 60% to 70% can be attributed to obesity. As early as the 1960s, the Framingham Heart Study found that for every 4.5 kg increase in body weight, systolic blood pressure increased by 4 mm Hg and obesity increased the risk of hypertension. The coexistence of obesity and hypertension can increase the difficulty of blood pressure control, promote the accumulation of multiple cardiovascular risk factors and increase the risk of cardiovascular and cerebrovascular diseases [1]. In recent years, the prevalence of hypertension and obesity