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目的:探讨小剂量他达拉非对勃起功能障碍(ED)患者的自尊心、自信心和性关系的影响。方法:17例ED患者每晚口服他达拉非5 mg 12周,用配对t检验比较治疗前后自尊心和性关系问卷(SEAR)、勃起功能国际问卷-5(IIEF-5)和夜间阴茎勃起(NEVA测定)的情况。结果:治疗后SEAR评分、IIEF-5两者均明显提高(P<0.01);夜间阴茎勃起明显改善(P<0.05)。结论:每日小剂量口服他达拉非可显著提高ED患者的自尊心、自信心和性关系满意度,改善ED患者的夜间勃起功能,是治疗ED的有效措施。
Objective: To investigate the effect of low dose tadalafil on pride, confidence and sexual relationship in patients with erectile dysfunction (ED). Methods: 17 patients with ED were given tadalafil 5 mg every night for 12 weeks. The paired t-test was used to compare the scores of self-esteem and sexual relationship before and after treatment (SEAR), erectile dysfunction questionnaire-5 (IIEF-5) and nocturnal penile erection NEVA assay). Results: After treatment, both SEAR score and IIEF-5 were significantly increased (P <0.01). Penile erection at night was significantly improved (P <0.05). Conclusion: Small doses of daily oral administration of tadalafil can significantly improve ED patients ’self-esteem, self-confidence and sexual satisfaction, and improve ED patients’ nocturnal erectile function, which is an effective measure to treat ED.