目的观察甘利欣注射液治疗抗痨药物性肝损害的临床疗效。方法将45例诊断明确的抗痨药物性肝损害的患者,随机分为治疗组和对照组,治疗组24例,采用甘利欣注射液150mg加入5%～10%葡萄糖250ml,静脉滴注,1次/d,疗程15d;对照组21例,采用肝泰乐片口服,0.3/次,3次/d,疗程15d。结果治疗组有效率为91.7%,对照组有效率为66.7%,两组比较治疗组疗效优于对照组(P<0.05),并且治疗组未发现明显的不良反应。结论甘利欣注射液治疗抗痨药物性肝损害,降酶效果迅速,保肝作用明显,疗效满意。 Objective To observe the clinical curative effect of GanLiXin injection in treating anti-tuberculosis drug-induced liver damage. Methods Forty-five patients with clinically diagnosed anti-tuberculosis drug-induced liver damage were randomly divided into treatment group and control group. The treatment group consisted of 24 patients. 250mg of 5% ~ 10% glucose was injected into 150ml salvia miltiorrhiza injection, Times / d, treatment 15d; control group of 21 cases, the use of gantelle tablets orally, 0.3 / time, 3 times / d, treatment 15d. Results The effective rate of the treatment group was 91.7% and that of the control group was 66.7%. The curative effect of the two groups was better than that of the control group (P <0.05). No obvious adverse reactions were found in the treatment group. Conclusion Glycyrrhizin injection treatment of anti-TB drug-induced liver damage, rapid reduction of the effect of liver, liver protection effect is obvious, the effect is satisfactory.