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目的分析良性阵发性位置性眩晕(BPPV)合并梅尼埃病病例的临床特征及预后。方法 2009年7月至2011年12月我院神经内科确诊BPPV患者343例,收集上述患者的临床资料,随访6年,通过与同期特发性BPPV病例的比较,分析评价BPPV合并梅尼埃病病例的临床特征及预后情况。结果 343例BPPV患者中特发性BPPV305例,继发于其他病因者26例,合并有梅尼埃病者12例(3.5%)。与特发性BPPV患者相比,BPPV合并梅尼埃病患者的平均年龄为(59.83±6.12)岁,明显大于特发性BPPV患者的(53.99±12.37)岁,t=3.069,P=0.008;其BPPV复发率(83.3%)亦明显高于特发性BPPV的复发率(17.4%),χ~2=27.535,P<0.001;但两组病例性别、平均病程及受累半规管的分布差异均无统计学意义。结论 BPPV合并梅尼埃病的发生率为3.5%,BPPV多发生于梅尼埃病病程的后期,患病年龄相对较大,BPPV更容易出现复发。
Objective To analyze the clinical characteristics and prognosis of benign paroxysmal positional vertigo (BPPV) combined with Meniere’s disease. Methods From July 2009 to December 2011, 343 cases of BPPV were diagnosed in neurology department of our hospital. The clinical data of these patients were collected and followed up for 6 years. By comparing with idiopathic BPPV cases in the same period, we analyzed and evaluated BPPV complicated with Meniere’s disease Case of clinical features and prognosis. Results 343 cases of BPPV idiopathic BPPV in 305 cases, secondary to other causes of 26 cases, combined with Meniere’s disease in 12 cases (3.5%). Compared with idiopathic BPPV patients, BPPV combined with Meniere ’s disease had a mean age of (59.83 ± 6.12) years, significantly higher than that of idiopathic BPPV patients (53.99 ± 12.37) years, t = 3.069, P = 0.008; The BPPV recurrence rate (83.3%) was also significantly higher than that of idiopathic BPPV (17.4%), χ ~ 2 = 27.535, P <0.001. However, there was no difference in gender, Statistical significance. Conclusions The incidence of BPH combined with Meniere’s disease is 3.5%. BPPV mostly occurs in the late stage of Meniere’s disease. The age of onset is relatively large, and BPPV is more likely to recur.