克洛己新干混悬剂中主要成分为头孢克洛及盐酸溴己新,最早由美国开发研制,其中头孢克洛及盐酸溴己新的含量测定如参照国外的测定方法在同一个色谱条件系统中测定,两成分之间有干扰,分离效果差,重现性不好。为了控制该制剂的质量,本实验参考文献[1],以改进的高效液相色谱法(HPLC The main components of the new Krokus major suspension of cefaclor and bromhexine hydrochloride, the first developed by the United States, which cefaclor and bromhexine hydrochloride determination as determined by reference to foreign methods in the same chromatographic conditions System determination, there is interference between the two components, the separation effect is poor, poor reproducibility. In order to control the quality of the preparation, this experiment reference [1], with improved high performance liquid chromatography (HPLC