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目的 探讨心脏外科病人术前合并脑梗死与术后神经功能障碍的关系。方法 将术前合并脑梗死的择期心脏外科手术病人 31例作为研究组 ;随机择期心脏外科手术病人按研究组 1∶2配对做为对照组 ,共 6 2例。对照组术前无脑梗死病史 ,手术时间与相配对的研究组相近。两组手术由同一组医生完成。结果 研究组术后清醒时间为 6 .5± 5 .0h ,明显长于对照组的 4 .6± 2 .9h(P <0 .0 5 ) ;研究组术后谵妄和脑梗死的发生率为 2 9.0 %和2 6 .1% ,明显高于对照组的 6 .5 %和 1.6 % (P <0 .0 1)。结论 术前合并脑梗死的心脏外科病人术后更易并发神经功能障碍
Objective To investigate the relationship between preoperative cerebral infarction and neurological dysfunction in cardiac surgery patients. Methods Thirty-one elective cardiac surgery patients with preoperative cerebral infarction were enrolled in this study. Patients randomized to elective cardiac surgery were assigned to a control group of 1: 2 with a total of 62 patients. The control group had no history of cerebral infarction before surgery, and the operation time was similar to that of matched study group. Two groups of surgery by the same group of doctors to complete. Results The postoperative awake time of the study group was 6.5 ± 5.0 hours, which was significantly longer than that of the control group (4.6 ± 2.9 hours, P <0.05). The incidence of delirium and cerebral infarction in the study group was 2 9.0% and 26.1%, respectively, which were significantly higher than those in the control group (6.5% vs 1.6%, P <0.01). Conclusions Cardiac surgery patients with preoperative cerebral infarction are more likely to develop neurological dysfunction after surgery