采用脉冲辐解技术 ,杜醌作参比物 ,通过改变鬼臼毒素、去甲表鬼臼毒素和 VP-1 6的浓度 ,控制其阴离子向杜醌电子转移的速度 ,测得了鬼臼毒素、去甲表鬼臼毒素和 VP-1 6的单电子还原电位分别为 -3 1 0 ,-3 3 9和 -3 3 4m V,揭示了鬼臼毒素及其衍生物作为抗肿瘤药物的辐射增敏机理 . By using pulsed radiolysis technology, the quinone was used as a reference substance. By changing the concentration of podophyllotoxin, noradrenopterin and VP-1 6 and controlling the electron transfer rate from the anion to the quinone, the podophyllotoxin, The single electron reduction potentials of podophyllotoxin and VP-1 6 were -3 1 0, -3 3 9 and -3 3 4 mV, respectively, revealing that the increase of podophyllotoxin and its derivatives as anti-tumor drugs Sensitive mechanism.