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Objective:The aim of the study was to observe the characters and differences of the inner and outer parts ofprostate gland,the prostatic cancer lesions in inner and outer parts of prostate glands by transrectal contrast enhanced ultra-sonography (TRCEUS) in order to provide valuable information for diagnosing of prostatic cancers.Methods:The ultrasoundcontrast agent was SonoVue (from Bracoo Company,Italian).Instrument adopted Esaote Company Technos DU8 (transrectalultrasonography).We observed the starting and ending times oftransrectal contrast enhancement in the normal prostate innergland group (16 cases),normal prostate outer gland group (16 cases),and the prostatic cancer lesions in inner gland group(8 cases) as well as in outer gland group (11 cases),respectively.Results:There was no significant difference in the startingtime of the normal prostate glands between the inner gland and outer gland groups (P ＞ 0.05),likewise no significant differ-ence between the cancer lesions in the inner gland and outer gland groups (P ＞ 0.05),but starting times of the cancer lesionsin both groups were earlier than those of the normal prostate inner and outer glands groups (P ＜ 0.01).The ending time ofenhancement was no significant difference among all groups (P ＞ 0.05).Conclusion:The earlier starting time of contrastenhancement in prostatic cancer lesions by TRCEUS has important value of distinguishing the cancer lesions from normalprostate glands.It is helpful to diagnose the prostatic cancer lesions.