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据估计全球约有3.5亿人感染乙型肝炎病毒(HBV),文献报道在原发性慢性肾炎中,血清HBV感染标志物阳性率约为40%。HBV感染人体后,可以通过直接或间接的方式导致肾炎的发生,诊断有赖于血液及肾活检组织免疫荧光检查。目前,肾病界对HBV相关性肾炎(HBV-GN)的诊断标准尚存分歧,国内主要依据1989年HBV相关性肾炎座谈会拟定的诊断标准。然而,临床实践有证据表明现有诊断标准存在诸多缺陷,本文就学者对此进行的相关有益的探索研究作一综述。
It is estimated that about 350 million people worldwide are infected with hepatitis B virus (HBV). In the literature, the positive rate of serum HBV infection markers in primary chronic nephritis is about 40%. HBV infection of the human body, can be directly or indirectly caused by the occurrence of nephritis, the diagnosis depends on the blood and renal biopsy tissue immunofluorescence. At present, the diagnostic criteria for nephrotic nephritis (HBV-GN) are still different in the nephrology community. The diagnostic criteria of the HBV-related nephritis symposium in 1989 are mainly based on the diagnostic criteria in China. However, there is evidence in clinical practice that there are many shortcomings in the existing diagnostic criteria. This article reviews some useful exploration and research done by scholars.