目的:观察伴有后巩膜葡萄肿（PS）的高度近视黄斑裂孔性视网膜脱离（MHRD）患眼玻璃体切割手术（PPV）中PS边缘视网膜激光光凝的临床疗效。方法:2017年1月至2019年6月于天津市眼科医院住院接受PPV治疗的伴有PS的MHRD患者49例49只眼纳入研究。其中，男性13例13只眼，女性36例36只眼。所有患眼均行最佳矫正视力（BCVA）、光相干断层扫描检查。BCVA检查采用标准对数视力表进行，统计时换算为最小分辨角对数（logMAR）视力。采用随机数余数分组法将患眼随机分为PS边缘视网膜激光组（激光组）、常规手术组（常规组），分别为25、24只眼。常规组、激光组患眼logMAR BCVA分别为1.87±0.28、1.80±0.37，差异无统计学意义（n t=0.604 ，n P=0.551 ）。常规组患眼行23G PPV，手术中曲安奈德染色，剥除视网膜前膜，吲哚青绿辅助染色，剥除后极部黄斑区内界膜（ILM ），手术中详查周边部视网膜，如存在视网膜变性区则行激光光凝加固，经黄斑裂孔排出视网膜下液后硅油填充。激光组患眼除按照常规组手术步骤进行外，于PS边缘行视网膜激光光凝2~3排。手术后平均随访时间（8.34±3.21 ）个月。观察视网膜复位率、黄斑裂孔闭合率、BCVA以及两组患眼的手术次数。计数资料比较采用n χ2检验或Fisher确切概率；计量资料比较采用独立样本n t检验。n 结果:首次手术后，常规组、激光组患眼视网膜复位分别为17 （70.8%，17/24）、24 （96.0%，24/25 ）只眼；激光组患眼视网膜复位率高于常规组，差异有统计学意义（n χ2=3.984，n P=0.046 ）。末次随访时，两组患眼视网膜均复位。常规组、激光组患眼黄斑裂孔闭合分别为15 （62.5%，15/24）、19 （76.0%，19/25）只眼；两组患眼黄斑裂孔闭合率比较，差异无统计学意义（n χ2=1.051，n P=0.305 ）。常规组、激光组患眼logMAR BCVA分别为1.20±0.47、1.08±0.39；与手术前logMAR BCVA比较，差异均有统计学意义（n t=2.899、5.327 ，n P=0.001、0.000 ）；两组患眼间logMAR BCVA比较，差异无统计学意义（n t=0.675 ，n P=0.506 ）。常规组、激光组患眼平均手术次数分别为（2.63±0.88）、（2.08±0.28）次；两组患眼平均手术次数比较，差异有统计学意义（n t=3.003 ，n P=0.006 ）。n 结论:与常规PPV比较，手术中联合PS边缘视网膜激光光凝可有效提高首次手术后视网膜复位率，降低重复手术次数。“,”Objective:To observe the outcome of posterior staphyloma (PS) marginal retinal photocoagulation in pars plana vitrectomy (PPV) for high myopia macular hole retinal detachment eyes accompanied with PS.Methods:From January 2017 to June 2019, 49 patients (49 eyes) with high myopia macular hole retinal detachment accompanied with PS who were undergone PPV operation from Tianjin Eye Hospital were included in this study. There were 13 males (13 eyes) and 36 females (36 eyes). All patients underwent best corrected visual acuities (BCVA) and optical coherence tomography examinations. The standard logarithmic visual acuity chart was used for BCVA examination, and the visual acuity was converted to minimum resolution angle in logarithmic (logMAR) when recorded. The patients were randomly divided into two groups according to surgical options: conventional PPV with internal limiting membrane (ILM) peeling (group A, 24 eyes), PS marginal retinal photocoagulation in PPV with ILM peeling (group A, 25 eyes). The mean preoperative logMAR BCVA of group A and B were 1.87±0.28 and 1.80±0.37, the difference was not statistically significant (n t=0.604, n P=0.551). The patients in the group A received 23G PPV, triamcinolone acetonide staining during the operation, the epiretinal membrane was peeled off, indocyanine green assisted staining, the posterior macular ILM was peeled off, and the peripheral retina was examined in detail during the operation. Areas with retinal degeneration were reinforced by laser photocoagulation, and the subretinal fluid was drained through the macular hole and filled with silicone oil. The eyes of the group B were subjected to retinal photocoagulation for 2 to 3 rows at the edge of the PS in addition to the usual surgical procedures. The average follow-up time was 8.34±3.21 months. Surgical outcome were estimated by the average number of operation, retinal reattachment rate, macular hole closure rate and BCVA. The n χ2 test or Fisher exact probability was used to compare the count data. Independent sample n t test was used to compare the measurement data.n Results:Retinal reattachment was obtained in 17 eyes (70.8%, 17/24) and 24 eyes (96.0%, 24/25) in group A and B after first surgery respectively, the difference was statistically significant (n χ2=3.984, n P=0.046). Final retinal reattachment was obtained in all 49 eyes. Final macular hole closure was in 15 eyes (62.5%, 15/24) and 19 eyes (76.0%, 19/25) in group A and B, respectively, the difference was not statistically significant (n χ2=1.051, n P=0.305). The mean postoperative logMAR BCVA of group A (1.20±0.47) and B (1.08±0.39) were all improved than preoperative BCVA, the differences were all statistically significant (n t=2.899, 5.327; n P=0.001, 0.000), the differences of mean postoperative logMAR BCVA between two groups was not statistically significant (n t=0.675, n P=0.506). The mean number of operation of group A (2.63±0.88) was more than group B (2.08±0.28), the difference was statistically significant (n t=3.003, n P=0.006).n Conclusion:In comparison with conventional PPV, combined PS marginal retinal photocoagulation can improve retinal reattachment rate after first surgery, and reduce the number of reoperations.