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目的 :探讨参芪地黄方对慢性肾功能衰竭 (CRF)脾肾两虚证患者脂质代谢的影响。方法 :对4 8例 CRF脾肾两虚证患者于治疗前后进行血脂及脂蛋白 a[Lp(a) ]检测。结果 :治疗前 CRF脾肾两虚证患者 CHO、TG、LDL、L p(a)均明显高于正常水平 ,HDL明显低于正常水平 ,经参芪地黄方治疗后 ,CHO、TG、LDL、Lp(a)均显著降低 (P<0 .0 5 ) ,HDL显著升高 (P<0 .0 5 )。结论 :提示参芪地黄方可改善CRF脾肾两虚证患者脂质代谢紊乱状态
Objective: To investigate the effect of Shenqi Dihuang Recipe on lipid metabolism in chronic renal failure (CRF) patients with spleen and kidney deficiency. Methods : Blood lipid and lipoprotein a [Lp(a)] were detected in 48 patients with CRF spleen and kidney deficiency before and after treatment. Results: Before treatment, CHO, TG, LDL, and L p (a) in patients with CRF spleen and kidney deficiency were significantly higher than normal levels, and HDL was significantly lower than normal. After treatment with Shenqidihuang, CHO, TG, LDL, Lp(a) decreased significantly (P<0.05) and HDL increased significantly (P<0.05). Conclusion: It is suggested that Shenqi Dihuang Fang can improve the disorder of lipid metabolism in patients with CRF spleen and kidney deficiency.