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本文用免疫组化和图象分析的方法,从病理形态结合功能代谢的角度观察分析了51例子宫绒毛膜癌。发现-hCG含量高者,其细胞多以合体滋养细胞(ST)为主,且呈丛状生长并摸拟胎盘绒毛排列,癌细胞多同步发育;反之,STf-hCG含量低者,癌细胞则多以细胞滋养细胞和(或)中间型滋养细胞为主且呈片块状,细胞排列紊乱,发育不同步(P<0.05～0.01)。本结果提示,绒癌的病理形态与其功能代谢间有着十分微妙的关系。作者认为对绒癌等病理形态与生物学行为相关性较差的肿瘤,应引入机能形态学和动力形态学的观点。
In this paper, immunohistochemistry and image analysis methods, from the perspective of pathological morphology combined with functional metabolism analysis of 51 cases of uterine choriocarcinoma. The results showed that the majority of cells with high content of hCG had more syncytiotrophoblasts (STs) and showed plexiform growth and mimic placenta villus arrangement, with more simultaneous development of cancer cells. Conversely, the content of STf-hCG was lower in cancer cells Most of the cells and / or trophoblast trophoblast mainly in the form of lumps, cells arranged disorder, development is not synchronized (P <0.05 ~ 0.01). The results suggest that the pathological morphology of choriocarcinoma and its functional metabolism has a very delicate relationship. The authors believe that on the choriocarcinoma and other pathological morphology and biological behavior of poor tumors, the introduction of functional morphology and dynamic morphological point of view.