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目的探讨分析颅内血管外皮瘤的诊断、治疗及预后。方法对1997-2006年间收治的18例颅内血管外皮细胞瘤就其临床和影像学表现、病理学特点、治疗及随访结果进行回顾性分析。结果18例病人共行手术23次,全切10例,次全切9例,部分切除4例。术后辅助传统放疗6例,辅助γ-刀治疗3例。15例原发病例中5例复发,平均复发时间76.75个月。发生颅内转移2例,发生神经系统外转移2例。结论颅内血管外皮细胞瘤不同于脑膜瘤,有较高的局部复发率,并可以发生神经轴和神经系统外转移,争取手术全切+剂量不少于50Gy的辅助放疗应作为常规的治疗方案。对于颅内血管外皮细胞瘤病人需终生随访。
Objective To investigate the diagnosis, treatment and prognosis of intracranial hemangiopericytoma. Methods 18 cases of intracranial hemangiopericytoma admitted from 1997 to 2006 were retrospectively analyzed on the clinical and imaging features, pathological features, treatment and follow-up results. Results Twenty-eight patients underwent 23 operations in total, 10 cases underwent complete subtotaling, 9 cases underwent subtotectomy and 4 cases underwent partial resection. Postoperative adjuvant traditional radiotherapy in 6 cases, adjuvant γ-knife treatment in 3 cases. Of the 15 cases, 5 cases relapsed with an average recurrence time of 76.75 months. There were 2 cases of intracranial metastases and 2 cases of extranodal metastases. Conclusions Intracranial hemangiopericytoma is different from meningioma and has a high local recurrence rate. It may occur outside the nerve axis and the outside of the nervous system. Surgical radiotherapy should be performed as a complete regimen of adjuvant radiotherapy at a dosage of not less than 50 Gy . For intracranial hemangiopericytoma patients need lifelong follow-up.