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目的探讨合理的诊断与治疗方法对宫颈上皮内瘤变(CIN)的临床价值。方法经宫颈刮片与阴道镜宫颈病理活检确诊的宫颈上皮内瘤变患者共120例,117例患者行宫颈环形电切术(LEEP),3例CINⅢ级患者LEEP后追加筋膜外子宫全切除术,并对全部患者随访2 a。结果 120例宫颈上皮内瘤变行LEEP及子宫全切术病理结果CINⅠ~Ⅲ分别为50例、32例、18例,CINⅡ~Ⅲ20例。随访术后3个月内CIN的患者宫颈大部分恢复如初,有5例患者于6个月内行第2次LEEP,LEEP一次成功率为95.73%(112/117),随访2a未发现CIN复发的病例。结论 LEEP具有创伤小、费用低、术后恢复快的优点,是目前治疗宫颈病变的较好方法,同时有预防早期宫颈癌价值。
Objective To investigate the clinical value of reasonable diagnosis and treatment of cervical intraepithelial neoplasia (CIN). Methods A total of 120 patients with cervical intraepithelial neoplasia diagnosed by cervical smear and colposcopy cervical biopsy were enrolled. 117 patients underwent LEEP and 3 patients with LEIN after LEEP. All patients were followed up for 2 years. Results The pathological results of LEEP and total hysterectomy in 120 cases of cervical intraepithelial neoplasia were 50 cases, 32 cases, 18 cases and 20 cases of CIN Ⅱ ~ Ⅲ. During the follow-up period, most patients with CIN returned to their original state within 3 months after operation. The second LEEP was performed in 5 patients within 6 months. The first successful rate of LEEP was 95.73% (112/117). No recurrence of CIN was found at follow-up Case. Conclusions LEEP has the advantages of small trauma, low cost and quick recovery after operation. It is a good method to treat cervical lesions at the same time and has the value of preventing early cervical cancer.