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目的 评价超声引导经皮微波固化疗法在肝癌的应用。方法 采用改良的超声引导经皮微波固化疗法 (percutaneousmicrowavecoagulationtherapy ,PMCT)治疗肝癌 12例 ,包括肝细胞性肝癌 7例 ,转移性肝癌 5例 ,共 16个结节 ,直径 1 5～ 6 4cm ,平均 3 8cm ,其中直径大于 3cm的结节 6个。结果 经首次治疗 ,随访 3～ 10个月 (平均 8 1个月 ) ,14个结节完全坏死 ,局部复发结节 2个。另外肝内远处多发转移 2例 ,单发转移 1例。局部复发及远处单发转移者经再次PMCT亦获得治愈。PMCT前后肝脏功能无明显改变。结论 通过适当延长微波辐射时间和采用多针多点组合辐射的方法 ,PMCT不仅治疗小肝癌疗效确切 ,亦能有效杀灭直径 3cm以上的癌灶。
Objective To evaluate the application of ultrasound-guided percutaneous microwave curing in liver cancer. Methods Improved ultrasound-guided percutaneous microwave coagulation therapy (PMCT) was used to treat 12 cases of hepatocellular carcinoma including 7 cases of hepatocellular carcinoma and 5 cases of metastatic hepatocellular carcinoma. A total of 16 nodules with a diameter of 15 to 64 cm were obtained. 8 cm, of which 6 are larger than 3 cm in diameter. Results After the first treatment, follow-up of 3 to 10 months (average of 81 months), 14 nodules completely necrotic, local recurrence of nodules. In addition, there were two cases of distant metastases in the liver and one case of single metastasis. Patients with local recurrence and distant metastases were cured by repeated PMCT. There was no significant change in liver function before and after PMCT. Conclusion By appropriately prolonging the time of microwave irradiation and adopting the multi-needle and multi-point combination radiation method, PMCT can not only treat the small hepatocellular carcinoma but also effectively kill the tumors with a diameter of more than 3 cm.