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艾滋病(获得性免疫缺损综合证,AIDS)患者因卡氏肺囊虫性肺炎接受SMZ-TMP治疗时常出现副作用。据报道,发生率达83%,而无艾滋病的卡氏肺囊虫性肺炎患者仅14%出现副作用。 SMZ-TMP对神经系统的副作用包括头痛、抑郁及幻觉,正常人中罕见,艾滋病患者中已报道的极少。80例接受SMZ-TMP治疗的艾滋病患者中,仅1例有灶性癫痫发作。另有报道2例服用SMZ-TMP的艾滋病患者出现共济失调。另一组18例中1例发生眩晕。本文报道4例因卡氏肺囊虫性肺炎服用SMZ-TMP的艾滋病患者出现一过性震颤。
AIDS (Acquired Immunodeficiency Syndrome, AIDS) Patients with Pneumocystis carinii pneumonia receive SMZ-TMP treatment often with side effects. It has been reported that the incidence of 83%, while only 14% of patients without Pneumocystis carinii pneumonia have AIDS side effects. Side effects of SMZ-TMP on the nervous system include headaches, depression and hallucinations, rare in normal people and very few in AIDS patients. Only 80 of the 80 HIV-infected patients who received SMZ-TMP had focal seizures. Another report of 2 cases of AIDS patients taking SMZ-TMP ataxia. Another group of 18 cases of vertigo occurred in 1 case. This article reports 4 cases of Pneumocystis carinii pneumonia due to taking SMZ-TMP AIDS patients had a transient tremor.