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乳腺癌是全世界女性最常见恶性肿瘤,严重危害妇女的健康。腋窝淋巴结受累情况为乳腺癌重要的预后因素。前哨淋巴结活组织检查(SLNB)可减少腋窝淋巴结清扫(ALND)术后并发症,并可准确评估腋窝淋巴结临床阴性乳腺癌患者的淋巴结转移状态,已成为乳腺癌的规范化手术之一,并被广泛用于乳腺癌腋窝淋巴结的分期诊断。目前,SLNB在技术较为成熟的乳腺外科团队已取得较为满意的成功率和假阴性率,但其在基层医院的推广仍面临一定困难,尤其是前哨淋巴结相关定位技术,对操作技巧及术者经验都有较高的要求。笔者就SLNB在早期乳腺癌治疗中临床应用的最新进展作一综述,并探讨SLNB在基层医院应用的可行性。
Breast cancer is the most common malignancy in the world for women, seriously endangering women’s health. Axillary lymph node involvement is an important prognostic factor in breast cancer. Sentinel lymph node biopsy (SLNB) can reduce the postoperative complications of axillary lymph node dissection (ALND) and accurately assess the lymph node metastasis in patients with clinically negative breast cancer of axillary lymph node. It has become one of the standardized procedures for breast cancer and has been widely used Staging for diagnosis of axillary lymph nodes in breast cancer. At present, SLNB has achieved satisfactory success rates and false-negative rates in the more mature breast surgery team, but it still faces some difficulties in the promotion of primary hospitals. In particular, SLNB is associated with positioning techniques for sentinel lymph nodes, Have higher requirements. The author reviews the latest clinical application of SLNB in the treatment of early breast cancer and discusses the feasibility of using SLNB in primary hospital.