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在传统的中医药中用桑树叶治疗“消渴”。作者曾报道桑树叶提取物对链脲佐菌素(STZ)引起的糖尿病小鼠具有很强的降血糖作用,不溶于乙醇的组分作用明显强于溶于乙醇的组分。Asano 等人已从桑树叶中分离出含 N 糖化合物,并确证了其结构。但是,至今未见有关这些化合物的降血糖作用的报道。因此,在本文中作者观察了含 N 糖化合
In traditional Chinese medicine, mulberry leaves are used to treat “diabetes.” The authors have reported that mulberry leaf extract has a strong hypoglycemic effect on streptozotocin (STZ)-induced diabetic mice, and the ethanol-insoluble components are significantly stronger than the ethanol-soluble components. Asano et al. have isolated N-sugar compounds from Mulberry leaves and confirmed their structure. However, no reports of hypoglycemic effects of these compounds have been reported so far. Therefore, in this article, the authors observed that