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目的分析硝苯地平联合硫酸镁治疗妊娠高血压患者的疗效。方法选取2015年4月~2016年4月我院收治的妊娠高血压患者128例作为研究对象,采用掷筛子法将其随机分为基础组与综合组,各64例。基础组患者仅接受硫酸镁治疗,而综合组患者在其基础上联合硝苯地平进行治疗,记录两组患者的疗效,并观察两组的分娩结局。结果经抗妊娠高血压治疗后,综合组的降压总有效率为96.88%(62/64),基础组的抗血压总有效率为67.19%(43/64),综合组的治疗疗效明显优于基础组,差异有统计学意义(P<0.05)。综合组的妊娠结局为顺产55例、剖宫产9例,其中发生产后出血1例、新生儿窒息1例;而基础组顺产36例、剖宫产28例,其中发生产后出血7例、新生儿窒息5例、巨大儿2例。明显可知,综合组的妊娠结局比基础组的理想,差异有统计学意义(P<0.05)。结论硝苯地平联合硫酸镁治疗妊娠高血压患者的综合疗效确切,并显著改善其妊娠结局,降低了新生儿窒息的发生几率,该综合疗法显著,值得应用于临床。
Objective To analyze the curative effect of nifedipine and magnesium sulfate in patients with pregnancy induced hypertension. Methods From April 2015 to April 2016, 128 cases of pregnancy-induced hypertension admitted to our hospital were selected as the research objects, which were randomly divided into basic group and comprehensive group by sieving method, each 64 cases. The patients in the basic group received magnesium sulfate only. The patients in the combined group were treated on the basis of nifedipine. The curative effect of both groups was recorded and the delivery outcomes of the two groups were observed. Results After antihypertensive treatment, the total effective rate was 96.88% (62/64) in the combined group and 67.19% (43/64) in the basic group. The curative effect of the combined group was superior In the basic group, the difference was statistically significant (P <0.05). In the combined group, the pregnancy outcome was 55 cases of cesarean section, 9 cases of cesarean section, including 1 case of postpartum hemorrhage and 1 case of neonatal asphyxia. In the basic group, 36 cases were cesarean, 28 cases were cesarean, including 7 cases of postpartum hemorrhage, Asphyxia in 5 cases, 2 cases of giant children. Obviously, the comprehensive group of pregnancy outcomes than the basic group ideal, the difference was statistically significant (P <0.05). Conclusion Nifedipine combined with magnesium sulfate in the treatment of patients with pregnancy-induced hypertension has definite curative effect, significantly improves the pregnancy outcome and reduces the incidence of neonatal asphyxia. The combination therapy is significant and worthy of clinical application.