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给大鼠按500和250 mg/kg灌胃鹿茸多糖,对醋酸型、应激型和幽门结扎型胃溃疡皆有明显的抗溃疡作用,但对消炎痛型溃疡无效。鹿茸多糖对五肽胃泌素引起的胃酸增多,有明显抑制作用,但对组织胺和毛果芸香碱所致的胃酸增多均无影响。对预先用阿斯匹林处理的大鼠胃酸和胃液中的PGE_2含量也无影响。
Rats given 500 and 250 mg / kg of pilose antler polysaccharide, acetic acid type, stress and pylorus ligation gastric ulcer Jieyou obvious anti-ulcer effect, but indomethacin-type ulcer is invalid. Antler polysaccharides on pentagastrin caused by increased gastric acid, a significant inhibitory effect, but histamine and pilocarpine caused by increased gastric acid had no effect. There was also no effect on the content of PGE 2 in gastric acid and gastric juice pretreated with aspirin.